Case Number 6863
Request Date 25/07/2019
Completion Date 15/08/2019

 

Details of the Request

The diagnosis and treatment of Homozygous Familial Hypercholesterolaemia (HoFH) at Ashford & St Peter's Hospitals NHSF Trust.

 

1. Does Ashford & St Peter's Hospitals NHSF Trust diagnose patients with Homozygous Familial Hypercholesterolaemia (HoFH)? Y/N

a. If yes, does your trust diagnose adult patients, paediatric patients or both?

b. How many patients in the last calendar year have you diagnosed with this condition?

Please provide where available (and applicable) a breakdown by Adult and/or Paediatric Patients.

 

c. Which of the following tests/diagnostic procedures do you use at Ashford & St Peter's Hospitals NHSF Trust in relation to the diagnostics of HoFH?

 

For these tests, which ones are you able to carry out “in house”?

Of those carried out elsewhere, where are patients referred to have the testing carried out?

 

For answers please use table below.

  • Cascade Genetic/DNA Tests
  • Dutch Lipid Clinic Network (DLCN) criteria
  • Simon Broome diagnostic criteria
  • Family History
  • Cholesterol / LDL Blood Testing
  • Other (please specify details of name of test

 

Test Name:

  • Cascade Genetic / DNA Tests
  • Dutch Lipid Clinic Network (DLCN) criteria
  • Simon Broome Diagnostic Criteria
  • Family History
  • Cholesterol / LDL Blood Testing
  • Other (please specify)
  • Test used for HoFH diagnosis at this trust (Y/N)
  • Test carried out by trust In-house for diagnosis of HoFH (Y/N)
  • Details of referral organisation/location for those tests that cannot be carried out by the trust.

 

Details of the Response

1. Does Ashford & St Peter's Hospitals NHSF Trust diagnose patients with Homozygous Familial Hypercholesterolaemia (HoFH)?

a. If yes, does your trust diagnose adult patients, paediatric patients or both?

  • Adults = Yes
  • Paediatrics = No

 

b. How many patients in the last calendar year have you diagnosed with this condition? Please provide where available (and applicable) a breakdown by Adult and/or Paediatric Patients.

  • Adults = 0
  • Paediatrics = Unavailable

 

c. Which of the following tests / diagnostic procedures do you use at Ashford & St Peter's Hospitals NHSF Trust in relation to the diagnostics of HoFH? For these tests, which ones are you able to carry out “in house”? Of those carried out elsewhere, where are patients referred to have the testing carried out?

Test Name Test used for HoFH diagnosis at this trust Test carried out by trust In-house for diagnosis of HoFH Details of referral organisation/location for those tests that cannot be carried out by the trust.
Cascade Genetic/DNA Tests Y N Bristol Genetics Laboratory Pathology Sciences Southmead Hospital Bristol, BS10 5NB
Dutch Lipid Clinic Network (DLCN) criteria N N  
Simon Broome Diagnostic Criteria Y Y  
Family History Y Y
Cholesterol/LDL Blood Testing Y Y  
Other (please specify) N N  

 

2. Does Ashford & St Peter's Hospitals NHSF Trust treat patients with Homozygous Familial Hypercholesterolaemia (HoFH)?

a. If no, please specify where patients diagnosed with HoFH are referred to for treatment. Please specify Trust/Organisation Name and Hospital Name where possible.

  • Adult: No, Hammersmith Hospital
  • Paediatric: No, St George’s Hospital Tooting

 

b. If yes, does your trust treat adult patients, paediatric patients or both?

N/A

 

i. If your trust doesn’t treat a subgroup (Adult or Paediatric), to which organisation are this sub group referred to for treatment? Please specify Trust/Organisation Name and Hospital Name where possible.

St George’s Hospital, Tooting

 

c. How many patients in the last calendar year have received treatment for HoFH at Ashford & St Peter's Hospitals NHSF Trust? Please provide where available (and applicable) a breakdown by Adult and/or Paediatric Patients.

N/A

 

d. For HoFH patients requiring Apheresis, are you able to carry out this procedure at Ashford & St Peter's Hospitals NHSF Trust?

No

 

i. If no, to which organisation(s) do you refer patients to for Apheresis treatment and how many patients are referred to these sites? Please list by trust name and hospital site where available, and where possible/applicable please breakdown patient referrals by Adult and Paediatric.

  • Adult = Hammersmith Hospital
  • Paediatric = St George’s Hospital, Tooting

 

ii. If yes, how many HoFH patients in the past calendar year have been treated by Apheresis by Ashford & St Peter's Hospitals NHSF Trust? Please where possible (and applicable) provide with break down by Adult and Paediatric Patients.

N/A